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InfoSanità

GIMBE^®

Workshop
Decisioni Cliniche
e Prove di Efficacia
Terza edizione

Rimini, 25-26 marzo 2006

8 crediti ECM

in collaborazione con

Gli articoli non disponibili in full text possono essere richiesti a: info@gimbe.org

Il TSH aumentato: “troppo” o “troppo poco”.
Conduttori: Antonino Cartabellotta, Alessandro Di Pasquale
Discussant: Gianni Garozzo, Mario Parenti, Michele Zini

• Slides

• Evidence appraised

  • Linee guida
    • Prodigy. November 2005
    • US Preventive Service Taske Force
      • Screening for Thyroid Disease: Recommendation Statement. Ann Intern Med 2004;140:125-127
      • Screening for subclinical thyroid dysfunction in nonpregnant adults: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 2004;140:128-41
    • Surks MI, Ortiz E, Daniels GH, Sawin CT, Col NF, Cobin RH, et al. Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA 2004;291:228-38.
    • AACE Thyroid Task Force. American Association of Clinical Endocrinologists medical guidelines for clinical practice for the evaluation and treatment of hyperthyroidism and hypothyroidism. Endocr Pract 2002 Nov-Dec
      • NGC
  • Evidence summaries
    • Nygaard B. Primary hypothyroidism. Clinical Evidence, January 2005
  • Revisioni sistematiche
  • Villar HCCE, Saconato H, Valente O, Atallah AN. Thyroid hormone replacement for subclinical hypothyroidism. (Protocol) The Cochrane Database of Systematic Reviews 2006, Issue 1
  • Revisioni non sistematiche
    • Wilson GR, Curry RW Jr.  Subclinical thyroid disease. Am Fam Physician 2005;72:1517-24
    • Ibay AD, Bascelli LM, Nashelsky J. Management of subclinical hypothyroidism. Am Fam Physician 2005;71:1763-4
    • Roberts CG, Ladenson PW. Hypothyroidism. Lancet 2004;363:793-803.
    • Col NF, Surks MI, Daniels GH. Subclinical thyroid disease: clinical applications. JAMA 2004;291:239-43
    • Kaplan MM, Sarne DH, Schneider AB. In search of the impossible dream? Thyroid hormone replacement therapy that treats all symptoms in all hypothyroid patients. J Clin Endocrinol Metab 2003;88:4540-2
  • Ricerca primaria (RCTs ed altri studi)
  • Roos A, Linn-Rasker SP, van Domburg RT, et al. The starting dose of levothyroxine in primary hypothyroidism treatment: a prospective, randomized, double-blind trial. Arch Intern Med 2005;165:1714-20
  • Escobar-Morreale HF, Botella-Carretero JI, Gomez-Bueno M, et al. Thyroid hormone replacement therapy in primary hypothyroidism: a randomized trial comparing L-thyroxine plus liothyronine with L-thyroxine alone. Ann Intern Med 2005;142:412-24.
  • Monzani F, Caraccio N, Kozakowa M, et al. Effect of levothyroxine replacement on lipid profile and intima-media thickness in subclinical hypothyroidism: a double-blind, placebo-controlled study. J Clin Endocrinol Metab 2004;89:2099-106
  • Clyde PW, Harari AE, Getka EJ, et al .Combined levothyroxine plus liothyronine compared with levothyroxine alone in primary hypothyroidism: a randomized controlled trial. JAMA 2003;290:2952-8

La gestione ambulatoriale del paziente con insufficienza renale: il Medico di Famiglia è un optional?

Conduttori: Antonino Cartabellotta, Alessandro Di Pasquale
Discussant: Leonardo Cagnoli, Modesto Fantini

• Slides

• Evidence appraised

  • Linee guida

    • National Kidney Foundation.

      • K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification and stratification. Am J Kidney Dis, 2002

      • Managing Dyslipidemias in Chronic Kidney Disease. Am J Kidney Dis, April 2003

      • Clinical Practice Guidelines on Hypertension and Antihypertensive Agents in Chronic Kidney Disease. Am J Kidney Dis, May 2004

    • Renal Association

      • UK Guidelines for Identification, Management and Referral. Sept 2005

        • eGuide

        • Concise guide

        • Full version

  • Revisioni sistematiche

  • Cochrane

    • Fouque D, Wang PH, Laville M, Boissel JP. Low protein diets for chronic renal failure in non diabetic adults. The Cochrane Database of Systematic Reviews 2006, Issue 4

  • Non-Cochrane

    • Casas JP, Chua W, Loukogeorgakis S, et al. Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis. Lancet 2005;366:2026-33

    • Jafar TH, Schmid CH, Landa M, et al. Angiotensin-converting enzyme inhibitors and progression of nondiabetic renal disease: a meta-analysis of patient-level data. Ann Intern Med 2001;135:73-87

      • Record DARE

  • Revisioni non sistematiche

    • Snyder S, Pendergraph B. Detection and evaluation of chronic kidney disease. Am Fam Physician 2005;72:1723-32

    • Meguid El Nahas A, Bello AK. Chronic kidney disease: the global challenge. Lancet 2005;365:331-40

    • Stigant C, Stevens L, Levin A. Nephrology: 4. Strategies for the care of adults with chronic kidney disease. CMAJ 2003;168:1553-60

    • Clase CM, Garg AX, Kiberd BA. Classifying kidney problems: can we avoid framing risks as diseases? BMJ 2004;329:912-5

Il follow-up oncologico: tra prassi consolidate, sgradite evidenze e conflitti professionali.
Conduttori: Antonino Cartabellotta, Alessandro Di Pasquale
Discussant: Paolo Fattori, Marco Grassi

• Slides

• Evidence appraised

  • Linee guida
    • National Comprensive Care Network (NCCN)  Clinical Practice Guidelines in Oncology
      • Breast Cancer.Ver. 2. 2006
    • SIGN
      • Management of breast cancer in women. January, 2006
    • American Society of Clinical Oncology (ASCO)
      • 2005 Update of Recommended Breast Cancer Surveillance Guidelines (in press)
      • 1998 Update of Recommended Breast Cancer Surveillance Guidelines. J Clin Oncol 1999;17:1080-1082
        • Smith TJ. The American Society of Clinical Oncology Recommended Breast Cancer Surveillance Guidelines can be done in a routine office visit. J Clin Oncol 2005;23:6807
    • Institute for Clinical Systems Improvement (ICSI)
      • Breast cancer treatment. Sept 2005
    • Health Canada's Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer
      • Clinical practice guidelines for the care and treatment of breast cancer: follow-up after treatment for breast cancer (summary of the 2005 update). CMAJ 2005;172:1319-20
        • Full guideline
    • Associazione Italiana di Oncologia Medica (AIOM)
      • Neoplasie della Mammella. Settembre, 2005
    • Centro di Prevenzione Oncologico, Regione Piemonte
      • Tumore della mammella. Luglio 2002
    • Centro di Valutazione per l'Efficacia dell'Assistenza Sanitaria (CeVEAS)
      • Carcinoma Mammario, Dicembre 2000
  • Revisioni sistematiche
  • Rojas MP, Telaro E, Russo A, et al. Follow-up strategies for women treated for early breast cancer. The Cochrane Database of Systematic Reviews 2006, Issue 1
  • Revisioni non sistematiche
    • Sturgeon C. Practice guidelines for tumor marker use in the clinic. Clin Chem 2002;48:1151-9
  • Ricerca primaria (RCTs ed altri studi)
  • Grunfeld E, Levine MN, Julian JA, et al. Randomized trial of long-term follow-up for early-stage breast cancer: a comparison of family physician versus specialist care. J Clin Oncol 2006;24:848-55
  • Khatcheressian JL, Smith TJ. Related Articles, Links Randomized trial of long-term follow-up for early-stage breast cancer: a comparison of family physician versus specialist care. J Clin Oncol 2006;24:835-7

FANS, Coxib ed oppioidi: come non perdere la rotta fra effetti collaterali ed effetti classe.
Conduttori: Antonino Cartabellotta, Alessandro Di Pasquale
Discussant: Paolo Angelini, Angelo Corvetta, William Raffaeli

• Slides

New Evidence on your desk

Conduttori: Antonino Cartabellotta, Alessandro Di Pasquale

• Caratteristiche della ricerca clinica

• Slides