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• Report 5^a Conferenza Nazionale GIMBE^®. 7 febbraio 2010

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Dalla letteratura internazionale

• BMJ, 6 marzo
  • Meta-analysis of individual participant data: rationale, conduct, and reporting

• BMJ, 27 febbraio
  • Publishing information about ongoing clinical trials for patients
  • The routine use of patient reported outcome measures in healthcare settings

• N Engl J Med, 25 febbraio
  • Serving Two Masters — Conflicts of Interest in Academic Medicine

• JAMA, 24 febbraio
  • Registering Clinical Trial Results: The Next Step

• CMAJ, 23 febbraio
  • Measuring performance is essential to patient-centred care

• Arch Intern Med, 22 febbraio
  • Decreasing Hospital Costs While Maintaining Quality: Can It Be Done?
  • Pharmaceutical Industry Support and Residency Education: A Survey of Internal Medicine Program Directors

• Lancet, 20 febbraio
  • Biological, clinical, and ethical advances of placebo effects

• BMJ, 20 febbraio
  • The prognosis for research
  • Registration of observational studies
  • Has guideline development gone astray? Yes
  • Has guideline development gone astray? No
  • Ten steps towards improving prognosis research

• Ann Intern Med, 16 febbraio
  • Improving Patient Care. Frequency of Inappropriate Medical Exceptions to Quality Measures

• PLoS Med, 16 febbraio
  • Guidance for Developers of Health Research Reporting Guidelines

• Lancet, 13 febbraio
  • Evidence-based medicine in China

• BMJ, 13 febbraio
  • Higher hospital volume and specialisation

• CMAJ, 12 febbraio
  • Knowledge creation: synthesis, tools and products
  • The knowledge-to-action cycle: identifying the gaps
  • Adapting clinical practice guidelines to local context and assessing barriers to their use
  • Developing and selecting interventions for translating knowledge to action
  • Selecting educational interventions for knowledge translation
  • Monitoring use of knowledge and evaluating outcomes

• JAMA, 10 febbraio
  • Replicating High-Quality Medical Care Organizations

• BMJ, 6 febbraio
  • Will financial incentives and penalties improve hospital care?
  • Preparing raw clinical data for publication: guidance for journal editors, authors, and peer reviewer

• N Engl J Med, 4 febbraio
  • Comparative Effectiveness and Health Care Spending — Implications for Reform

• JAMA, 3 febbraio
  • Safe Electronic Health Record Use Requires a Comprehensive Monitoring and Evaluation Framework
  • Electronic Health Records in the Age of Social Networks and Global Telecommunications
  • Evidence-Based Medicine Requires Appropriate Clinical Context

• PLoS, 2 febbraio
  • Ghostwriting at Elite Academic Medical Centers in the United States

• Lancet, 30 gennaio
  • The perils of journal and supplement publishing
  • Should protocols for observational research be registered?
  • A flexible blueprint for the future of drug development
  • Comparative effectiveness research stalls in the USA
  • A framework for mandatory impact evaluation to ensure well informed public policy decisions

• BMJ, 30 gennaio
  • NICE and new: appraising innovation

• JAMA, 27 gennaio
  • Continuing Medical Education: Let the Guessing Begin

• PLoS, 26 gennaio
  • Science Must Be Responsible to Society, Not to Politics

• Arch Intern Med, 25 gennaio
  • Drug Safety: Are We Making Progress?: Comment on "Pooled Analysis of Rofecoxib Placebo-Controlled Clinical Trial Data"

• BMJ, 23 gennaio
  • Use of multiperspective qualitative interviews to understand patients’ and carers’ beliefs, experiences, and needs

• N Engl J Med, 21 gennaio
  • Accelerating the Use of Electronic Health Records in Physician Practices

• BMJ, 16 gennaio
  • Should healthy volunteers in clinical trials be paid according to risk? Yes
  • Should healthy volunteers in clinical trials be paid according to risk? No

• JAMA, 13 gennaio
  • Funding of US Biomedical Research, 2003-2008
  • Insights From Trends in Biomedical Research Funding

• CMAJ, 12 gennaio
  • Disseminate time-sensitive research faster
  • Registering systematic reviews

• Arch Intern Med, 11 gennaio
  • Systematic Review of Guidelines on Cardiovascular Risk Assessment: Which Recommendations Should Clinicians Follow for a Cardiovascular Health Check?
  • Screening for High-Risk Cardiovascular Disease: A Challenge for the Guidelines

• BMJ, 9 gennaio
  • Is primary care research a lost cause?

• Ann Intern Med, 5 gennaio
  • Spending More to Save More: Interventions to Promote Adherence

• PLoS, 5 gennaio
  • Are Patents Impeding Medical Care and Innovation?

• Lancet, 2 gennaio
  • The financial challenge facing the NHS
  • Drug development for neglected diseases: pharma's influence

• BMJ, 2 gennaio
  • Aubrey Blumsohn: Academic who took on industry
  • Bias in identifying and recruiting participants in cluster randomised trials: what can be done?

• N Engl J Med, 31 dicembre
  • Public Reporting of Discharge Planning and Rates of Readmissions

• JAMA, 23/30 dicembre
  • Strength of Study Evidence Examined by the FDA in Premarket Approval of Cardiovascular Devices
  • Strengthening Institutional Review Board Review of Highly Innovative Interventions in Clinical Trials

• BMJ, 19 dicembre. Christmas issue

• N Engl J Med, 17 dicembre
  • The Agenda for Continuing Medical Education — Limiting Industry's Influence

• JAMA, 16 dicembre
  • Heterogeneity Is Not Always Noise: Lessons From Improvement
  • Mentoring: What's in a Name?

• Lancet, 11 dicembre
  • How to reduce prescribing errors

• BMJ, 5 dicembre
  • On the origin of variation
  • Is the conflict of interest unacceptable when drug companies conduct trials on their own drugs? Yes
  • Is the conflict of interest unacceptable when drug companies conduct trials on their own drugs? No
  • Good publication practice for communicating company sponsored medical research: the GPP2 guidelines

• Lancet, 5 dicembre
  • COPE's retraction guidelines

• JAMA, 2 dicembre
  • Effectiveness of Public Report Cards for Improving the Quality of Cardiac Care: The EFFECT Study: A Randomized Trial
  • The Need for Large-Scale Randomized Evidence Without Undue Emphasis on Small Trials, Meta-analyses, or Subgroup Analyses

• BMJ, 28 novembre
  • Applicability and generalisability of published results of randomised controlled trials and non-randomised studies evaluating four orthopaedic procedures: methodological systematic review

• N Engl J Med, 26 novembre
  • A Difficult Balance — Pain Management, Drug Safety, and the FDA

• JAMA, 25 novembre
  • Association of Hospital Primary Angioplasty Volume in ST-Segment Elevation Myocardial Infarction With Quality and Outcomes
  • Requirements and Definitions in Conflict of Interest Policies of Medical Journals
  • The Rational Clinical Examination
    • Acute-Onset Floaters and Flashes: Is This Patient at Risk for Retinal Detachment?
  • Therapeutic Innovations, Diminishing Returns, and Control Rate Preservation

• PLoS Med, 24 novembre
  • Evaluating eHealth: How to Make Evaluation More Methodologically Robust

• Arch Intern Med, 23 novembre
  • Pooled Analysis of Rofecoxib Placebo-Controlled Clinical Trial Data: Lessons for Postmarket Pharmaceutical Safety Surveillance
  • Bringing the FDA's Information to Market

• BMJ, 21 novembre
  • Safety Alerts: National Patient Safety Agency: combining stories with statistics to minimise harm

• JAMA, 18 novembre
  • The Rational Clinical Examination
    • Does This Patient With Palpitations Have a Cardiac Arrhythmia?

• PLoS Med, 17 novembre
  • The Unintended Consequences of Clinical Trials Regulations
  • How Can We Support the Use of Systematic Reviews in Policymaking?

• Lancet, 14 novembre
  • Explaining the unbiased creation of treatment comparison groups

• BMJ, 14 novembre
  • The tyranny of power: is there a better way to calculate sample size?

• N Engl  J Med, 12 novembre
  • Outcome Reporting in Industry-Sponsored Trials of Gabapentin for Off-Label Use

• JAMA, 11 novembre
  • Shared Medical Regulation in a Time of Increasing Calls for Accountability and Transparency: Comparison of Recertification in the United States, Canada, and the United Kingdom
  • Clinical Research Sites—The Underappreciated Component of the Clinical Research System
  • The Purpose and Limits to Professional Self-regulation

• Lancet, 7 novembre
  • Teaching responsible conduct of research
  • The FDA's poor oversight of postmarketing studies
  • Homoeopathy: not a matter for drug-regulatory authorities

• BMJ, 7 novembre
  • How long does it take to train a surgeon?
  • Diagnosis in General Practice
    • Using probabilistic reasoning

• N Engl J Med, 4 novembre
  • Uniform Format for Disclosure of Competing Interests in ICMJE Journals

• PLoS Med, 3 novembre
  • Mandatory Disclosure of Pharmaceutical Industry-Funded Events for Health Professionals

• Ann Intern Med, 3 novembre
  • Much Cheaper, Almost as Good: Decrementally Cost-Effective Medical Innovation

• Ann Intern Med, 3 novembre
  • Much Cheaper, Almost as Good: Decrementally Cost-Effective Medical Innovation

• BMJ, 31 ottobre
  • Improving patient safety through training in non-technical skills
  • The need to confront variation in practice
  • Risk of bias versus quality assessment of randomised controlled trials: cross sectional study

• N Engl J Med, 29 ottobre
  • Lost in Transmission — FDA Drug Information That Never Reaches Clinicians
  • Implementing Evidence-Based Health Policy in Washington State

• JAMA, 28 ottobre
  • Patient-Centered Care and Preference-Sensitive Decision Making
  • Reform of Continuing Medical Education: Investments in Physician Human Capital

• CMAJ, 27 ottobre
  • Uniform format for disclosure of competing interests in ICMJE journals

• Arch Intern Med, 26 ottobre
  • Adverse Events in Randomized Trials: Neglected, Restricted, Distorted, and Silenced
  • Reporting of Safety Results in Published Reports of Randomized Controlled Trials

• BMJ, 23 ottobre
  • Using patient experience within pay for performance programmes
  • Use of serial qualitative interviews to understand patients’ evolving experiences and needs
  • Statistics Notes: Analysis of continuous data from small samples
  • Applying for ethical approval for research in the United Kingdom

• Lancet, 23 ottobre
  • Uniform format for disclosure of competing interests in ICMJE journals

   

• Ann Intern  Med, 20 ottobre
  • Randomized Trials and Technology Assessment

• BMJ, 17 ottobre
  • Disclosure of competing interests
  • Don’t give up the ghost
  • The unpalatable truth about ethics committees

• Lancet, 17 ottobre
  • StaR Child Health: an initiative for RCTs in children

• JAMA, 14 ottobre
  • Beyond Outcomes—The Appropriateness of Surgical Care
  • Multihospital Collaborations for Surgical Quality Improvement
  • Shared Accountability, Appropriateness, and Quality of Surgical Care

• CMAJ, 13 ottobre
  • Bridging the gaps: getting evidence into practice
  • Improving the quality of care for infants: a cluster randomized controlled trial
  • Integration of evidence from multiple meta-analyses: a primer on umbrella reviews, treatment networks and multiple treatments meta-analyses

• Arch Intern Med, 12 ottobre
  • Can the Food and Drug Administration Ensure That Our Pharmaceuticals Are Safely Manufactured?

• Lancet, 10 ottobre
  • PRISMAtic reporting of systematic reviews and meta-analyses

• BMJ, 10 ottobre
  • Applying quality improvement approaches to health care

• N Engl J Med 8 ottobre
  • Accuracy of Conflict-of-Interest Disclosures Reported by Physicians
  • The Confirmatory Trial in Comparative-Effectiveness Research

• JAMA, 7 ottobre
  • Using Effectiveness and Cost-effectiveness to Make Drug Coverage Decisions: A Comparison of Britain, Australia, and Canada
  • Disruption and Innovation in Health Care

• BMJ, 4 ottobre
  • Closing the evidence gap in integrative medicine
  • Filtering Medline for a clinical discipline: diagnostic test assessment framework
  • Quality Improvement Report: The role of specialists in managing the health of populations with chronic illness: the example of chronic kidney disease

• N Engl J Med, 1 ottobre
  • Opportunities and Challenges for the NIH — An Interview with Francis Collins

• PLoS Med, 29 settembre
  • Considering Usual Medical Care in Clinical Trial Design

• Lancet, 26 settembre
  • Surgical research: the reality and the IDEAL
  • Surgical research: act 3, answers
  • Benchmarking in surgical research
  • Series. Surgical Innovation and Evaluation
    • 1. Evaluation and stages of surgical innovations
    • 2. Challenges in evaluating surgical innovation
    • 3. No surgical innovation without evaluation: the IDEAL recommendations
  • Standardised metrics for global surgical surveillance

• BMJ, 26 settembre
  • Can financial incentives improve health equity?
  • What can we learn from German health incentive schemes?
  • Use of qualitative methods alongside randomised controlled trials of complex healthcare interventions: methodological study
  • Critical reflections on the rise of qualitative research
  • Diagnosis in General Practice: Iterative diagnosis

• N Engl J Med, 24 settembre
  • New, but Not Improved? Incorporating Comparative-Effectiveness Information into FDA Labeling
  • British Lessons on Health Care Reform
  • The Delayed-Start Study Design

• JAMA, 23/30 settembre. Theme Issue: Medical Education
  • Tools for Direct Observation and Assessment of Clinical Skills of Medical Trainees: A Systematic Review
  • Why Medical Educators May Be Failing at Feedback

• BMJ, 19 settembre
  • Does improving quality of care save money?
  • The effects of excluding patients from the analysis in randomised controlled trials: meta-epidemiological study

• Lancet, 19 settembre
  • Are medical journals getting better—or worse?

• Ann Intern Med, 15 settembre
  • Method for Establishing Authorship in a Multicenter Clinical Trial

• PLoS, 15 settembre
  • The GRADE System for Rating Clinical Guidelines
  • Grading Quality of Evidence and Strength of Recommendations: A Perspective

• JAMA, 9 settembre
  • Comparisons of Citations in Web of Science, Scopus, and Google Scholar for Articles Published in General Medical Journals
  • The Journal Impact Factor Denominator: Defining Citable (Counted) Items
  • Electronic Medical Records at a Crossroads: Impetus for Change or Missed Opportunity?

• PLoS, 8 settembre
  • Trial Publication after Registration in ClinicalTrials.Gov: A Cross-Sectional Analysis
  • Ghostwriting: The Dirty Little Secret of Medical Publishing That Just Got Bigger

• BMJ, 5 settembre
  • The effects of payment by results
  • Disagreements in meta-analyses using outcomes measured on continuous or rating scales: observer agreement study
  • Has payment by results affected the way that English hospitals provide care? Difference-in-differences analysis

• Lancet, 5 settembre
  • Dispelling myths about drug research

• JAMA, 3 settembre
  • Life-Science Research Within US Academic Medical Centers
  • Comparison of Registered and Published Primary Outcomes in Randomized Controlled Trials
  • Evolving From Reductionism to Holism: Is There a Future for Systems Medicine?
  • Assessing the Appropriateness of Care—Its Time Has Come
  • Cost Shifting Does Not Reduce the Cost of Health Care
  • Researchers, Funding, and Priorities: The Razor's Edge

• Ann Intern Med, 1 settembre
  • Improving Patient Care. Comparing Costs and Quality of Care at Retail Clinics With That of Other Medical Settings for 3 Common Illnesses
  • An Electronic Practice-Based Network for Observational Comparative Effectiveness Research
  • Design of a National Distributed Health Data Network
  • Discussing Treatment Preferences With Patients Who Want "Everything"
  • Toward Reuse of Clinical Data for Research and Quality Improvement: The End of the Beginning?

• BMJ, 29 agosto
  • New methods to deal with publication bias
  • Novel methods to deal with publication biases: secondary analysis of antidepressant trials in the FDA trial registry database and related journal publications
  • The double jeopardy of clustered measurement and cluster randomisation

• Lancet, 29 agosto
  • Self-plagiarism: unintentional, harmless, or fraud?

• N Engl J Med, 27 agosto
  • Disclosure of Financial Relationships to Participants in Clinical Research

• JAMA; 26 agosto
  • Setting Priorities for Patient Safety: Ethics, Accountability, and Public Engagement

• PLos Med, 25 agosto
  • The Effect of Alternative Graphical Displays Used to Present the Benefits of Antibiotics for Sore Throat on Decisions about Whether to Seek Treatment: A Randomized Trial
  • The Effect of Alternative Summary Statistics for Communicating Risk Reduction on Decisions about Taking Statins: A Randomized Trial
  • Making the “Right” Health Care Decisions: Why Values Matter

• Lancet, 22 agosto
  • NICE set to revise Quality and Outcomes Framework indicators
  • European Commission takes on Big Pharma

• BMJ, 22 agosto
  • BMJ pico for original research in the print BMJ

• N Engl J Med, 29 agosto
  • Multinational Medicines — Ensuring Drug Quality in an Era of Global Manufacturing

• JAMA, 19 agosto
  • Registries for Robust Evidence
  • Heart Failure Performance Measures and Outcomes: Real or Illusory Gains

• Ann Intern Med, 18 agosto
  • The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
  • Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

• PLoS Med, 18 agosto
  • Evaluating eHealth Interventions: The Need for Continuous Systemic Evaluation

• BMJ, 15 agosto
  • Evidence based implementation of complex interventions
  • Valuing health directly
  • Quality Improvement Report: A multifaceted strategy for implementation of the Ottawa ankle rules in two emergency departments
  • Diagnosis in General Practice: Clinical prediction rules

• N Engl J Med, 13 agosto
  • The New Sentinel Network — Improving the Evidence of Medical-Product Safety
  • Managing Drug-Risk Information — What to Do with All Those New Numbers
  • Premature Release of Data from Clinical Trials of Ezetimibe

• PLoS Med, 11 agosto
  • Can We Systematically Review Studies That Evaluate Complex Interventions?

• CMAJ, 10 agosto
  • Defining knowledge translation

• Arch Intern Med, 10/24 agosto
  • Do Hospitalists Improve Quality?
  • Building a Bayesian Bridge From Evidence to Guidelines: Comment on "Bayesian Classification of Clinical Practice Guidelines"

• BMJ, 8 agosto
  • Improving performance in the NHS
  • Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

• Lancet, 8 agosto
  • Getting to the heart of high-quality care

• Ann Intern Med, 4 agosto
  • Comparative Effectiveness Research: A Report From the Institute of Medicine
  • Rethinking Randomized Clinical Trials for Comparative Effectiveness Research: The Need for Transformational Change
  • Modeling Comparative Effectiveness and the Value of Research

• BMJ, 1 agosto
  • Making information about clinical trials publicly available

• Lancet, 1 agosto
  • Use of patient-reported outcomes in clinical practice

• Arch Intern Med, 27 luglio
  • Assessing the Value of a Diagnostic Test

• BMJ, 25 luglio
  • Inappropriate referencing in research
  • Measuring patients’ experiences and outcomes
  • How citation distortions create unfounded authority: analysis of a citation network

• Lancet, 25 luglio
  • If NICE was in the USA
  • Clinical experts or methodologists to write clinical guidelines?
  • The public health effect of economic crises and alternative policy responses in Europe: an empirical analysis
  • The decade of NICE

• N Engl J Med, 23 luglio
  • Prioritizing Comparative-Effectiveness Research — IOM Recommendations
  • Comparative-Effectiveness Research — Implications of the Federal Coordinating Council's Report
  • Effects of Pay for Performance on the Quality of Primary Care in England

• PLoS Med, 21 luglio
  • Can the Relationship between Doctors and Drug Companies Ever Be a Healthy One?
  • Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
  • The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration

• MJA, 20 luglio
  • Promoting evidence-based non-drug interventions: time for a non-pharmacopoeia?

• Lancet 18 luglio
  • Phase 0 trials: a platform for drug development?

• BMJ, 18 luglio
  • Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls
  • Statistics Notes: Parametric v non-parametric methods for data analysis

• Lancet, 11 luglio
  • Reporting genetic association studies: the STREGA statement
  • Reinventing primary health care: the need for systems integration

• JAMA, 8 luglio
  • FDA Performance Goals for Approving Drugs and Biologics
  • The Need for Improved Access to FDA Reviews
  • Possible Outcomes of Comparative Effectiveness Research
  • Beyond Information: Exploring Patients' Preferences
  • Resolving Unreported Conflicts of Interest

• CMAJ, 7 luglio
  • Competing interests of authors: We have revised our policy
  • Long-term trends in use of and expenditures for cardiovascular medications in Canada
  • Individualized electronic decision support and reminders to improve diabetes care in the community: COMPETE II randomized trial
  • Rational use of medications: If Canada can’t do it ...
  • Improving primary care for patients with complex chronic diseases: Can health information technology play a role?

• Ann Intern Med, 7 luglio
  • Improving Patient Care. Working Conditions in Primary Care: Physician Reactions and Care Quality
  • Medical Journal Editing: Who Shall Pay?

• BMJ, 4 luglio
  • Watching over the medical device industry
  • Errors in clinical reasoning: causes and remedial strategies
  • Diagnosis in General Practice: Test of time

• Lancet, 4 luglio
  • Avoidable waste in the production and reporting of research evidence

• JAMA, 1 luglio
  • The Obligation to Participate in Biomedical Research
  • Ethical Collection, Storage, and Use of Public Health Data: A Proposal for a National Privacy Protection
  • Building Bridges Between Medical Care and Public Health
  • The Case for Public Ownership of Patient Data
  • Exploring the Harmful Effects of Health Care

• Arch Intern Med, 22 giugno
  • Cost-effectiveness Analysis of an Established, Effective Procedure

• BMJ, 20 giugno
  • Palivizumab and the importance of cost effectiveness
  • Prognosis and prognostic research 4. Application and impact of prognostic models in clinical practice

• Lancet, 20 giugno
  • Could the UK lead the world in medical education and training?

• JAMA; 17 giugno
  • Does Comparative Effectiveness Have a Comparative Edge?

• Ann Intern Med, 16 giugno
  • Balancing Randomized Trials With Anecdote

• BMJ, 13 giugno
  • A model for NICE in the US
  • Standing up for safety
  • Prognosis and prognostic research 3. Validating a prognostic model

• N Engl J Med, 11 giugno
  • The FDA as a Public Health Agency

• PLoS Med, 9 giugno
  • In Global Health Research, Is It Legitimate To Stop Clinical Trials Early on Account of Their Opportunity Costs?

• Arch Intern Med, 8 giugno
  • Editorial Policies and Publication Bias: The Importance of Negative Studies
  • Improving the Primary Care–Specialty Care Interface: Getting From Here to There
  • A Typology of Specialists' Clinical Roles

• Lancet, 6 giugno
  • Incomplete reporting of research in academic press releases
  • Translating statistical findings into plain English

• BMJ, 6 giugno
  • International experience of paying for expensive medicines
  • Prognosis and prognostic research 2. Developing a prognostic model

• BMJ, 30 maggio
  • Prognosis and prognostic research: what, why, and how?

• JAMA, 27 maggio
  • Advancing 21st-Century Medical Professionalism

• CMAJ, 26 maggio
  • Disclosing errors that affect multiple patients

• Arch Intern Med, 25 maggio
  • Imaging Idolatry: The Uneasy Intersection of Patient Satisfaction, Quality of Care, and Overuse
  • Health Care Information Technology: A Cloud Around the Silver Lining?

• BMJ, 23 maggio
  • Safeguarding NHS standards
  • Global priorities for patient safety research
  • Reporting of sample size calculation in randomised controlled trials: review
  • Diagnosis in General Practice: Diagnosis using "test of treatment"

• N Engl 21 maggio
  • Controlling Conflict of Interest — Proposals from the Institute of Medicine

• JAMA, 20 maggio
  • Regulating the Safety of Pharmaceuticals: The FDA, Preemption, and the Public's Health

• BMJ, 16 maggio
  • Does the FDA have the authority to trump the Declaration of Helsinki?

• N Engl J Med, 14 maggio
  • Globalized Clinical Trials and Informed Consent

• JAMA, 13 maggio
  • The Chasm Between Intention and Achievement in Primary Care

• CMAJ, 12 maggio
  • A pragmatic–explanatory continuum indicator summary (PRECIS): a tool to help trial designers
  • Explaining pragmatic trials to pragmatic policy-makers

• PLoS, 12 maggio
  • Do Electronic Health Records Help or Hinder Medical Education?
  • No More Free Drug Samples?

• Arch Intern Med, 11 maggio
  • Time for the Medical Profession to Act: New Policies Needed Now on Interactions Between Pharmaceutical Companies and Physicians
  • Effect of Exposure to Small Pharmaceutical Promotional Items on Treatment Preferences

• Lancet, 9 maggio
  • A UK Google for guidelines

• N Engl J Med, 7 maggio
  • Does Comparative-Effectiveness Research Threaten Personalized Medicine?
  • Debate about Funding Comparative-Effectiveness Research
  • The Neglected Purpose of Comparative-Effectiveness Research

• JAMA, 6 maggio
  • Assessing Authority

• Ann Intern Med, 5 maggio
  • Press Releases by Academic Medical Centers: Not So Academic?
  • Ibn Sina and the Clinical Trial

• PLoS Med, 5 maggio
  • Preventing Bias in Cluster Randomised Trials
  • Evaluation and Recommendations on Good Clinical Laboratory Practice Guidelines for Phase I–III Clinical Trials

• Lancet, 2 maggio
  • NHS Evidence: better and faster access to information
  • An academia–industry partnership in health care

• CMAJ, 28 aprile
  • Medication errors in critical care: risk factors, prevention and disclosure
  • Managing evidence-based knowledge: the need for reliable, relevant and readable resources

• Arch Intern Med, 27 aprile
  • The Change We Need in Health Care

• BMJ, 25 aprile
  • Using financial incentives to achieve healthy behaviour
  • Diagnosis in General Practice: Diagnostic strategies used in primary care

• Lancet, 25 aprile
  • How ethical are for-profit institutional review boards?

• JAMA 22/29 aprile
  • Association of Physician Certification and Outcomes Among Patients Receiving an Implantable Cardioverter-Defibrillator
  • Management of Diseases Without Current Treatment Options: Something Can Be Done

• Ann Intern Med, 21 aprile
  • Using a Drug Facts Box to Communicate Drug Benefits and Harms: Two Randomized Trials
  • Communicating Drug Benefits and Risks Effectively: There Must Be a Better Way

• Med J Aust, 20 aprile
  • Liaison between public hospital staff and the pharmaceutical industry: guidance from the NSW Therapeutic Advisory Group
  • Doctors and the pharmaceutical industry: time for a national policy?

• BMJ, 18 aprile
  • Quality in primary health care: a multidimensional approach to complexity
  • Methodological problems in the use of indirect comparisons for evaluating healthcare interventions: survey of published systematic reviews

• Lancet, 18 aprile
  • Public disclosure of clinical research

• N Engl J Med, 16 aprile
  • Use of Electronic Health Records in U.S. Hospitals

• Arch Intern Med, 13 aprile
  • Scientific Evidence and Medical Practice: The "Drunkard's Walk"

• BMJ, 11 aprile
  • Practising safely in the foundation years

• Lancet, 11 aprile
  • The trouble with screening
  • The HRT controversy: observational studies and RCTs fall in line

• N Engl J Med, 9 aprile
  • Stimulating the Adoption of Health Information Technology
  • The NIH Stimulus — The Recovery Act and Biomedical Research
  • The Future of Research Funding in Academic Medicine

• JAMA, 8 aprile
  • Conflict of Interest, Disclosure, and Trial Reports

• Ann Intern Med, 7 aprile
  • Toward a 21st-Century Health Care System: Recommendations for Health Care Reform
  • Perspectives on Health Care Reform

• BMJ, 4 aprile
  • Measuring the quality of hospital care
  • Patients and the public deserve big changes in evaluation of drugs
  • Evidence of methodological bias in hospital standardised mortality ratios: retrospective database study of English hospitals
  • Written informed consent and selection bias in observational studies using medical records: systematic review

• N Engl J Med, 2 aprile
  • A To-Do List for the New FDA Commissioner
  • Safe Drugs and the Cost of Good Intentions

• JAMA, 1 aprile
  • Professional Medical Associations and Their Relationships With Industry: A Proposal for Controlling Conflict of Interest
  • A New Strategy to Improve Quality: Rewarding Actions Rather Than Measures

• BMJ, 28 marzo
  • Managing UK research data for future use
  • Teaching on a ward round

• N Engl J Med, 26 marzo
  • No Small Change for the Health Information Economy
  • Your Doctor's Office or the Internet? Two Paths to Personal Health Records

• JAMA, 25 marzo
  • Measuring Preventable Harm: Helping Science Keep Pace With Policy
  • Health Care Information Technology Vendors' "Hold Harmless" Clause: Implications for Patients and Clinicians
  • Ownership of Medical Information

• PLoS Med, 24 marzo
  • Guidelines for Field Surveys of the Quality of Medicines: A Proposal

• Lancet, 21 marzo
  • Medical education and professionalism
  • Protocols, probity, and publication
  • Opening up public health: a strategy of information and communication technology to support population health

• N Engl J Med, 19 marzo
  • An Uncertain Future for Cardiovascular Drug Development?

• CMAJ, 17 marzo
  • Research ethics review: Do it once and do it well

• Med J Aust, 16 marzo
  • Non-inferiority trials: determining whether alternative treatments are good enough

• BMJ, 14 marzo
  • Industry attack on academics
  • Patient and public involvement in chronic illness: beyond the expert patient

• JAMA, 11 marzo
  • Diagnostic Errors—The Next Frontier for Patient Safety

• Lancet, 7 marzo
  • Moving from research ethics review to research ethics systems in low-income and middle-income countries

• CMAJ, 3 marzo
  • Health research: measuring the social, health and economic benefits

• Ann Intern Med, 3 marzo
  • Improving Patient Care. Patient–Physician Connectedness and Quality of Primary Care
  • Systematic Review: Reliability of Compendia Methods for Off-Label Oncology Indications
  • Controlling Off-Label Medication Use
  • Compendia and Anticancer Therapy Under Medicare
  • Evaluating Off-Label Uses of Anticancer Drugs: Time for a Change

• Med J Aust, 16 marzo
  • Quality of prescribing decision support in primary care: still a work in progress
  • Quality of drug interaction alerts in prescribing and dispensing software
  • Identifying existing health care services that do not provide value for money

• Lancet, 28 febbraio
  • Comparative effectiveness research in the USA
  • Trade and health: an agenda for action
  • A vision statement on guideline development for respiratory disease: the example of COPD

• JAMA, 25 febbraio
  • Scientific Evidence Underlying the ACC/AHA Clinical Practice Guidelines
  • Reassessment of Clinical Practice Guidelines: Go Gently Into That Good Night

• PLoS Med, 24 febbraio
  • An Unbiased Scientific Record Should Be Everyone's Agenda

• Arch Intern Med, 23 febbraio
  • Unburdening the Difficult Clinical Encounter
  • Burden of Difficult Encounters in Primary Care: Data From the Minimizing Error, Maximizing Outcomes Study

• Lancet, 21 febbraio
  • Trade and Health 5 Trade, TRIPS, and pharmaceuticals

• BMJ, 21 febbraio
  • Beyond the impact factor

• N Engl J Med, 19 febbraio
  • Commercial versus Social Goals of Tracking What Doctors Do
  • Ethical and Scientific Implications of the Globalization of Clinical Research
  • Progress and Deficiencies in the Registration of Clinical Trials

• JAMA, 18 febbraio
  • Clinicians in Quality Improvement: A New Career Pathway in Academic Medicine

• Ann Intern Med, 17 febbraio
  • Improving Patient Care. Comparison of Methods for Delivering a Lifestyle Modification Program for Obese Patients: A Randomized Trial

• PLoS Med, 17 febbraio
  • Inadequate Dissemination of Phase I Trials: A Retrospective Cohort Study

• BMJ, 14 febbraio
  • New design rules for driving innovation in access to secondary care in the NHS
  • Use of primary care electronic medical record database in drug efficacy research on cardiovascular outcomes: comparison of database and randomised controlled trial findings
  • Publication guidelines for quality improvement studies in health care: evolution of the SQUIRE project

• JAMA, 12 febbraio
  • Science, Politics, and Values: The Politicization of Professional Practice Guidelines

• Lancet, 7 febbraio
  • The UK's NHS and pharma: from schism to symbiosis

• BMJ, 7 febbraio
  • Doctors, patients, and the pharmaceutical industry
  • Relationships with the drug industry: More regulation, greater transparency
  • Relationships with the drug industry: Collaboration to improve care
  • Relationships with the drug industry: Focus on better information
  • Relationships with the drug industry: Keep at arm’s length
  • Relationships with the drug industry: Build trust based on good science
  • How to webcast lectures and conferences

• N Engl J Med, 5 febbraio
  • Physician–Industry Relations — Will Fewer Gifts Make a Difference?
  • Limits on Medicare's Ability to Control Rising Spending on Cancer Drugs

• PLoS Med, 3 febbraio
  • What Should Be Done To Tackle Ghostwriting in the Medical Literature?
  • Neglected Disease Research and Development: How Much Are We Really Spending?

• Ann Intern Med, 3 febbraio
  • Improving Patient Care.A Reengineered Hospital Discharge Program to Decrease Rehospitalization: A Randomized Trial
  • Update on the Methods of the U.S. Preventive Services Task Force: Insufficient Evidence
  • STrengthening the REporting of Genetic Association Studies (STREGA): An Extension of the STROBE Statement

• Lancet, 31 gennaio
  • Over-the-counter medicines: in whose best interests?
  • UK doctors hail research excellence results
  • Principles for allocation of scarce medical interventions

• BMJ, 31 gennaio
  • Rationing new medicines in the UK
  • NICE goes global
  • Should NICE’s threshold range for cost per QALY be raised? Yes
  • Should NICE’s threshold range for cost per QALY be raised? No
  • NICE and the challenge of cancer drugs

• N Engl J Med, 29 gennaio
  • A Surgical Safety Checklist to Reduce Morbidity and Mortality in a Global Population

• JAMA, 28 gennaio
  • Why Guideline-Making Requires Reform

• Arch Intern Med, 26 gennaio
  • The Effects of Health Information Technology on Inpatient Care
  • Clinical Information Technologies and Inpatient Outcomes: A Multiple Hospital Study

• BMJ, 24 gennaio
  • Surgical safety checklists
  • What should clinicians do when faced with conflicting recommendations?

• N Engl J Med, 22 gennaio
  • Online Disclosure of Physician–Industry Relationships

• JAMA, 21gennaio
  • The Rational Clinical Examination. Does This Patient Have a Pleural Effusion?
  • How to Use an Article About Genetic Association: C: What Are the Results and Will They Help Me in Caring for My Patients?

• CMAJ, 20 gennaio
  • Defining and disseminating the hospital-at-home model
  • Avoiding hospital admission through provision of hospital care at home: a systematic review and meta-analysis of individual patient data

• BMJ, 17 gennaio
  • Patient reported outcome measures in trials
  • Readmissions as a result of adverse drug reactions in older people
  • Resource allocation—it’s a jungle out there
  • What can we learn from drug marketing efficiency?
  • The balance between marketing and safety
  • Reporting and interpretation of SF-36 outcomes in randomised trials: systematic review
  • Comorbidity and repeat admission to hospital for adverse drug reactions in older adults: retrospective cohort study
  • Evaluating service delivery interventions to enhance patient safety

• JAMA, 14 gennaio
  • Users' Guides to the Medical Literature. How to Use an Article About Genetic Association: B: Are the Results of the Study Valid?
  • Improving the Quality of Health Care: Who Is Responsible for What?

• BMJ, 9 gennaio
  • Changes to the regulation of drug prices in the UK
  • Devolution and divergence in UK health policies
  • Patients’ preferences within randomised trials: systematic review and patient level meta-analysis

• N Engl J Med, 8 gennaio
  • Money and the Changing Culture of Medicine
  • The Neurontin Legacy — Marketing through Misinformation and Manipulation

• JAMA, 7 gennaio
  • Users' Guides to the Medical Literature. How to Use an Article About Genetic Association: A: Background Concepts

• Lancet, 3 gennaio
  • Helsinki discords: FDA, ethics, and international drug trials

• BMJ, 3 gennaio
  • The rational clinical examination in emergency care
  • Innovations in publishing BMJ research
  • The future of the quality and outcomes framework
  • New format for BMJ research articles in print
  • Interpreting research findings to guide treatment in practice

• N Engl J Med, 1 gennaio
  • Communicating Medical News — Pitfalls of Health Care Journalism

• JAMA 24 / 31 dicembre
  • Physician Autonomy and Informed Decision Making: Finding the Balance for Patient Safety and Quality

• Lancet, 20 dicembre
  • De testimonio: on the evidence for decisions about the use of therapeutic interventions

• N Engl J Med, 18 dicembre
  • Revisiting Duty-Hour Limits — IOM Recommendations for Patient Safety and Resident Education
  • The Future of Primary Care — The Community Responds

• JAMA, 17 dicembre
  • Effect of Evidence-Based Feeding Guidelines on Mortality of Critically Ill Adults: A Cluster Randomized Controlled Trial
  • Implementing Nutrition Guidelines in the Critical Care Setting: A Worthwhile and Achievable Goal?

• Ann Intern Med, 16 dicembre
  • Systematic Reviews of Diagnostic Test Accuracy
  • Diagnostic Test Accuracy and Clinical Decision Making

• BMJ, 13 dicembre
  • How should health be defined?
  • Research funding goes metric
  • Should there be a ceiling on what percentage of GDP countries spend on health?
  • Discrepancies in sample size calculations and data analyses reported in randomised trials: comparison of publications with protocols

• Arch Intern Med, 8 / 22 dicembre
  • Integrated Monitoring Systems and Patient Safety: A Need for Further Study

• Lancet, 6 dicembre
  • Is clinical prevention better than cure?

• JAMA, 3 dicembre
  • Clinical Equivalence of Generic and Brand-Name Drugs Used in Cardiovascular Disease: A Systematic Review and Meta-analysis
  • Closing the Evidence Gap in the Use of Emerging Testing Technologies in Clinical Practice

• CMAJ, 2 dicembre
  • Can studies of harm be harmful?

• Ann Intern Med, 2 dicembre
  • Improving Patient Care. Active Bed Management by Hospitalists and Emergency Department Throughput
  • When Should a New Test Become the Current Reference Standard?
  • Narrative Review: Do State Laws Make It Easier to Say "I'm Sorry?"

• BMJ, 29 novembre
  • Role of routines in collaborative work in healthcare organisations
  • Recruitment to multicentre trials—lessons from UKCTOCS: descriptive study
  • Giving feedback in clinical settings

• JAMA, 26 novembre
  • Benefits and Risks of Drug Treatments: How to Combine the Best Evidence on Benefits With the Best Data About Adverse Effects

• PLoS Med, 25 novembre
  • Reporting Bias in Drug Trials Submitted to the Food and Drug Administration: Review of Publication and Presentation
  • Bias, Spin, and Misreporting: Time for Full Access to Trial Protocols and Results

• BMJ, 23 novembre
  • The UK quality and outcomes framework
  • Should we use regulation to demand improved public health outcomes from industry? Yes
  • Should we use regulation to demand improved public health outcomes from industry? No
  • Is health care getting safer? 
  • Patient safety indicators for England from hospital administrative data: case-control analysis and comparison with US data
  • Improving the reporting of pragmatic trials: an extension of the CONSORT statement

• JAMA, 19 novembre
  • Organizational Improvements to Enhance Modern Clinical Epidemiology

• Ann Intern Med, 18 novembre
  • Improving Patient Care. Healing Skills for Medical Practice

• Med J Aust, 17 novembre
  • Quality use of medicines: what does it mean for you?

• BMJ, 15 novembre
  • The BMJ Evidence Centre
  • Looking to Europe: German health care: a bit of Bismarck plus more science
  • Evidence Based Case Report: Aspirin in type 2 diabetes: is there any evidence base?

• Lancet, 15 novembre
  • More evidence needed for chronic conditions in children
  • Selective COX-2 inhibitors: where do we go from here?
  • Racial disparities in clinical trial enrolment

• N Engl J Med, 13 novembre
  • The Future of Primary Care: The Need for Reinvention
  • The Future of Primary Care: Sustaining Relationships
  • The Future of Primary Care: Transforming Practice
  • The Future of Primary Care: Reforming Physician Payment
  • The Future of Primary Care: Refocusing the System
  • The Future of Primary Care: Lessons from the U.K.
  • Perspective Roundtable: Redesigning Primary Care

• JAMA, 12 novembre
  • Translating New Medical Therapies Into Societal Benefit: The Role of Population-Based Outcome Studies

• PLoS Med, 11 novembre
  • Informed Consent and Shared Decision-Making: A Requirement to Disclose to Patients Off-Label Prescriptions

• BMJ, 8 novembre
  • Fresh thinking about the Declaration of Helsinki
  • Continuing medical education: What price education?
  • Cutting out human error
  • Regulation—the real threat to clinical research

• Lancet, 8 novembre
  • Can health equity become a reality?
  • Can we eliminate inequalities in coronary disease? Absolutely

• N Engl J Med, 6 novembre
  • Saying No Isn't NICE — The Travails of Britain's National Institute for Health and Clinical Excellence
  • Drug Development for Neglected Diseases — The Trouble with FDA Review Vouchers

• JAMA, 5 novembre
  • Glucose Lowering to Control Macrovascular Disease in Type 2 Diabetes: Treating the Wrong Surrogate End Point?

• CMAJ, 4 novembre
  • Revalidation of physicians in Canada: Are we passing the test?
  • Information exchange among physicians caring for the same patient in the community

• Ann Intern Med, 4 novembre
  • Composite Outcomes in Cardiovascular Research: A Survey of Randomized Trials
  • Publication Guidelines for Improvement Studies in Health Care: Evolution of the SQUIRE Project
  • Improving the Quality of Reporting Studies of Quality Improvement: The SQUIRE Guidelines

• Med J Aust, 3 novembre
  • Good Medical Practice: developing an Australian code

• BMJ, 1 novembre
  • The credit crisis and health care
  • Does this work for you?
  • Introduction of shared electronic records: multi-site case study using diffusion of innovation theory

• Lancet, 1 novembre
  • The state of health research worldwide
  • Protecting health during the economic crisis
  • Signposts to research for health

• PLoS Med 28 ottobre
  • Off-Label Promotion, On-Target Sales

• Lancet, 25 ottobre
  • The UK Panel of Research Integrity: a missed opportunity

• BMJ, 25 ottobre
  • New MRC guidance on evaluating complex interventions
  • Research methods and reporting
  • Translating evidence into practice: a model for large scale knowledge translation
  • Research Methods and Reporting 1. Developing and evaluating complex interventions: the new Medical Research Council guidance

• JAMA 22/29 ottobre
  • Safety-Related Regulatory Actions for Biologicals Approved in the United States and the European Union
  • Association of Patient Case-Mix Adjustment, Hospital Process Performance Rankings, and Eligibility for Financial Incentives
  • Prescription Drugs, Products Liability, and Preemption of Tort Litigation

• CMAJ, 21 ottobre
  • Use of evidence-based therapies after discharge among elderly patients with acute myocardial infarction
  • Factors associated with the use of evidence-based therapies after discharge among elderly patients with myocardial infarction
  • Indicators of quality of care for patients with acute myocardial infarction

• Med J Aust, 20 ottobre
  • A robust clinical review process: the catalyst for clinical governance in an Australian tertiary hospital

• BMJ, 18 ottobre
  • Clinical priority setting
  • Accountability for reasonableness: an update
  • Moving forward on rationing: an economic view

• JAMA, 15 ottobre
  • The Rational Clinical Examination. Will the History and Physical Examination Help Establish That Irritable Bowel Syndrome Is Causing This Patient's Lower Gastrointestinal Tract Symptoms?
  • The Professional Ethics of Billing and Collections
  • Progress in Evidence-Based Medicine
  • The Disconnect Between Practice Guidelines and Clinical Practice—Stressed Out

• BMJ, 11 ottobre
  • Recognising excellence, innovation, and integrity

• Lancet, 11 ottobre
  • Collapse of GMC hearing into research misconduct

• Ann Intern Med, 7 ottobre
  • Improving Patient Care.The Effect of a Quality Improvement Collaborative to Improve Antimicrobial Prophylaxis in Surgical Patients: A Randomized Trial

• PLoS, 7 ottobre
  • Why Current Publication Practices May Distort Science

• BMJ, 4 ottobre
  • Economic evaluation of health interventions
  • Communicating about screening

• Lancet, 4 ottobre
  • National and multinational prospective trial registers

• JAMA, 1 ottobre
  • News Media Coverage of Medication Research: Reporting Pharmaceutical Company Funding and Use of Generic Medication Names

• PLoS Med, 30 settembre
  • Making Sense of Non-Financial Competing Interests

• BMJ, 27 settembre
  • Evidence based medicine and the medical curriculum
  • Translational research

• N Engl J Med, 25 settembre
  • Identifying and Addressing Safety Signals in Clinical Trials

• PLoS Med, 23 settembre
  • Ethical and Practical Issues Associated with Aggregating Databases
  • Publication of Clinical Trials Supporting Successful New Drug Applications: A Literature Analysis

• CMAJ, 23 settembre
  • Exaggeration of treatment benefits using the "event-based" number needed to treat

• BMJ, 20 settembre
  • Qualitative Research 6. Critically appraising qualitative research
  • Teaching Rounds: Teaching in an ambulatory care setting

• N Engl J Med, 18 settembre
  • Beyond Pay for Perform

• N Engl J Med, 18 settembre
  • Beyond Pay for Performance — Emerging Models of Provider-Payment Reform

• BMJ, 13 settembre
  • The self controlled case series method
  • Local accountability in the NHS
  • Patient confidentiality and consent to publication
  • Contract Research Organisations: Truly independent research?
  • Gaining consent for publication in difficult cases involving children
  • Consent to publication—no absolutes
  • Consent and confidentiality in publishing—the view of the BMJ’s ethics committee
  • Implementation of computerised physician order entry (CPOE) and picture archiving and communication systems (PACS) in the NHS: quantitative before and after study
  • Qualitative Research 5.  Why use theories in qualitative research?

• JAMA, 10 settembre
  • Internet-Based Learning in the Health Professions: A Meta-analysis

• CMAJ, 9 settembre
  • The "number needed to treat" turns 20 — and continues to be used and misused

• Lancet, 6 settembre
  • The role and responsibilities of coauthors
  • Health impact assessments in the European Union

• BMJ, 6 settembre
  • Direct to consumer advertising of prescription drugs
  • Tackling health inequities
  • Effect of illicit direct to consumer advertising on use of etanercept, mometasone, and tegaserod in Canada: controlled longitudinal study
  • Qualitative Research 4. Discourse analysis

• JAMA, 3 settembre
  • New Developments in Managing Physician-Industry Relationships
  • Industry-Sponsored Clinical Research: A Broken System
  • Industry Support of Medical Education

• BMJ, 30 agosto
  • Continuing medical education in the 21st century
  • Sponsorship of Medical Education: Is the relationship between pharma and medical education on the rocks?
  • Continuing Medical Education: Pharma and CME: View from the US
  • Continuing Medical Education: End of the free lunch?
  • Rethinking continuing medical education
  • Qualitative Research 3. Qualitative research methodologies: ethnography

• Lancet, 30 agosto
  • Addressing the inequities in health: a new and vital mandate
  • Time to add health research to New Zealand's election agenda
  • Quality and outcomes framework: patient-centred?
  • Effect of financial incentives on inequalities in the delivery of primary clinical care in England: analysis of clinical activity indicators for the quality and outcomes framework

• JAMA, 27 agosto
  • Opportunities for Enhancing the FDA Guidance on Pharmacovigilance

• Lancet, 23 agosto
  • Welcome clinical leadership at NICE
  • Health economics and prioritising health care

• BMJ, 23 agosto
  • Measuring the quality of healthcare systems using composites
  • Self reported receipt of care consistent with 32 quality indicators: national population survey of adults aged 50 or more in England
  • Qualitative Research 2. Grounded theory, mixed methods, and action research

• N Engl J Med, 21 agosto
  • Shattuck Lecture: Health of the Nation — Coverage for All Americans
  • Health of the Nation — Coverage for All Americans

• JAMA, 20 agosto
  • A Historical Perspective of Pharmaceutical Promotion and Physician Education

• Ann Intern Med, 19 agosto
  • Appropriateness Criteria for Coronary Angiography in Angina: Reliability and Validity
  • The ADVANTAGE Seeding Trial: A Review of Internal Documents
  • Navigating Language Barriers under Difficult Circumstances
  • The Nomogram Epidemic: Resurgence of a Medical Relic
  • Assessing Appropriateness of Coronary Angiography: Another Step in Improving Quality
  • Seeding Trials: Just Say "No"

• Med J Aust, 18 agosto
  • Financial disclosure and clinical research: what is important to participants?

• Lancet, 16 agosto
  • Developments for funding clinical research in the UK
  • Merging evidence-based and mechanism-based medicine

• BMJ, 16 agosto
  • Qualitative Research 1. An introduction to reading and appraising qualitative research

• PLoS Med, 12 agosto
  • Children Are Not Just Small Adults: The Urgent Need for High-Quality Trial Evidence in Children

• Arch Intern Med, 11/25 agosto
  • Medical Records and Quality of Care in Acute Coronary Syndromes Results From CRUSADE

• Lancet, 9 luglio
  • A changed FDA?
  • Should newborn infants be excluded from multiple research studies?

• BMJ, 9 luglio
  • Open access to research
  • Providing information for patients
  • Use of GRADE grid to reach decisions on clinical practice guidelines when consensus is elusive
  • Interventions before consultations to help patients address their information needs by encouraging question asking: systematic review
  • Open access publishing, article downloads, and citations: randomised controlled trial

• N Engl J Med, 7 agosto
  • Disclosure of Industry Payments to Physicians
  • Medicare, Graduate Medical Education, and New Policy Directions

• Ann Intern Med, 5 agosto
  • Against Diagnosis

• BMJ, 2 agosto
  • Confronting therapeutic ignorance

• Lancet, 2 agosto
  • Progress towards revalidation of the UK medical profession

• CMAJ, 29 luglio
  • A guide for the design and conduct of self-administered surveys of clinicians

• BMJ, 28 luglio
  • How the internet is changing health care
  • Will the NHS strategic plan benefit patients?
  • A transatlantic review of the NHS at 60

• JAMA 25 luglio
  • The Next Step in Guideline Development: Incorporating Patient Preferences

• Med J Aust, 21 luglio
  • Pay for performance systems in general practice: experience in the United Kingdom
  • Information overload: what’s behind it, what’s beyond it?
  • The effect of advertising in clinical software on general practitioners’ prescribing behaviour
  • Measuring patient-reported outcomes: moving from clinical trials into clinical practice

• Lancet, 19 luglio
  • Protocol review at The Lancet
  • Selective reporting in clinical trials: analysis of trial protocols accepted by The Lancet

• N Engl J Med, 17 luglio
  • Exclusion of Patients from Pay-for-Performance Targets by English Physicians

• PLoS Med, 15 luglio
  • Next Stop, Don't Block the Doors: Opening Up Access to Clinical Trials Results

• CMAJ, 15 luglio
  • Direct-to-consumer advertising: end the compromise
  • Hospital mortality: when failure is not a good measure of success

• Ann Intern Med, 15 luglio
  • Improving Patient Care. Comparing Patient-Reported Hospital Adverse Events with Medical Record Review: Do Patients Know Something That Hospitals Do Not?

• Arch Intern Med, 15 luglio
  • What Do Certification Examinations Tell Us About Quality?
  • Shared Decision Making: Have We Missed the Obvious?
  • Relationship, Communication, and Efficiency in the Medical Encounter: Creating a Clinical Model From a Literature Review
  • Association Between Maintenance of Certification Examination Scores and Quality of Care for Medicare Beneficiaries

• BMJ, 12 luglio
  • Enhancing the quality and transparency of health research
  • The problem in setting research priorities: a layman’s experience

• N Engl J Med, 10 luglio
  • The (Slowly) Vanishing Prescription Pad

• JAMA, 9 luglio
  • Web Searching for Information About Physicians

• BMJ, 5 luglio
  • What does the future hold for the NHS at 60?

• N Engl J Med, 3 luglio
  • Electronic Health Records in Ambulatory Care — A National Survey of Physicians

• Ann Intern Med, 1 luglio
  • Improving Patient Care. Public Reporting of Antibiotic Timing in Patients with Pneumonia: Lessons from a Flawed Performance Measure
  • Surrogate Decision Making: Reconciling Ethical Theory and Clinical Practice

• Lancet, 28 giugno
  • The NHS: the next 60 years
  • Fighting plagiarism
  • Researcher identification: the right needle in the haystack
  • Primary endpoints for randomised trials of cancer therapy
  • What does a National Health Service mean in the 21st century?

• BMJ, 28 giugno
  • Effects of quality improvement collaboratives
  • Continuous publication
  • Are international medical conferences an outdated luxury the planet can’t afford? Yes
  • Are international medical conferences an outdated luxury the planet can’t afford? No
  • NHS at 60: How the NHS measures up
  • What is missing from descriptions of treatment in trials and reviews?
  • Evidence for the impact of quality improvement collaboratives: systematic review
  • Evidence Based Case Report: Pulmonary embolism in a patient taking clozapine

• JAMA, 25 giugno
  • Everyone's a Little Bit Biased (Even Physicians)

• PLoS Med, 24 giugno
  • Guidelines for Reporting Health Research: The EQUATOR Network's Survey of Guideline Authors

• Arch Intern Med, 23 giugno
  • Evaluating Quality in Small-Volume Hospitals
  • Why Patients Continue to Participate in Clinical Research

• BMJ, 21 giugno
  • Should the drug industry work with key opinion leaders? Yes
  • Should the drug industry work with key opinion leaders? No
  • Key opinion leaders: independent experts or drug representatives in disguise?
  • NHS at 60: A centrally funded health service, free at the point of delivery
  • Research methodology: Reasons or excuses for avoiding meta-analysis in forest plots

• Lancet, 21 giugno
  • Electronic health records

• N Engl J Med, 19 giugno
  • Over-the-Counter Sales of Statins and Other Drugs for Asymptomatic Conditions

• JAMA, 18 giugno
  • The Perfect Storm of Overutilization

• CMAJ, 17 giugno
  • Integrity at the Croatian Medical Journal

• Ann Intern Med, 17 giugno
  • Information on Cost-Effectiveness: An Essential Product of a National Comparative Effectiveness Program
  • A Menu without Prices
  • Cost-Effectiveness Information: Yes, It's Important, but Keep It Separate, Please!

• Med J Aust 16 giugno
  • Evidence-based advocacy: the public roles of health care professionals

• BMJ, 14 giugno
  • Placebo pills for children
  • NHS at 60: A comprehensive service

• Lancet, 14 giugno
  • Direct-to-consumer advertising under a different name

• N Engl J Med, 12 giugno
  • Redefining Quality — Implications of Recent Clinical Trials

• Arch Intern Med, 9 giugno
  • Improving Care Quality and Reducing Disparities: Physicians' Roles

• BMJ, 7 giugno
  • Assessing patients’ improvement in clinical trials
  • Should we use large scale healthcare interventions without clear evidence that benefits outweigh costs and harms? Yes
  • Should we use large scale healthcare interventions without clear evidence that benefits outweigh costs and harms? No
  • Product placement in the waiting room
  • NHS at 60: Universality, equity, and quality of care
  • Complex interventions or complex systems? Implications for health economic evaluation
  • Doctors’ versus patients’ global assessments of treatment effectiveness: empirical survey of diverse treatments in clinical trials

• JAMA, 4 giugno
  • Patient-Important Outcomes in Registered Diabetes Trials

• Med J Aust, 2 giugno
  • Human research ethics — a work in progress
  • Research governance: current knowledge among clinical researchers

• BMJ, 31 maggio
  • Audit: how to do it in practice

• N Engl J Med, 29 maggio
  • Exploiting a Research Underclass in Phase 1 Clinical Trials

• JAMA, 28 maggio
  • Relationship Between Regional Per Capita Medicare Expenditures and Patient Perceptions of Quality of Care
  • The Power of Prevention and What It Requires
  • Spending on Medical Care: More Is Better?

• PLoS Med, 27 maggio
  • How Do US Journalists Cover Treatments, Tests, Products, and Procedures? An Evaluation of 500 Stories
  • Disease Mongering Is Now Part of the Global Health Debate
  • False Hopes, Unwarranted Fears: The Trouble with Medical News Stories

• BMJ, 24 maggio
  • Quality improvement in the NHS
  • How to interpret figures in reports of clinical trials
  • Rating quality of evidence and strength of recommendations: Incorporating considerations of resources use into grading recommendations
  • Evidence Based Case Report: Does paracetamol cause hypertension?

• JAMA, 21 maggio
  • The Deregulatory Effects of Preempting Tort Litigation: FDA Regulation of Medical Devices
  • Tracing Biological Collections: Between Books and Clinical Trials
  • The "3T’s" Road Map to Transform US Health Care: The "How" of High-Quality Care

• Ann Intern Med, 20 maggio
  • Using Existing Systematic Reviews in Complex Systematic Reviews
  • The Science and Art of Deduction: Complex Systematic Overviews

• BMJ, 17 maggio
  • Should patients be able to pay top-up fees to receive the treatment they want? Yes
  • Should patients be able to pay top-up fees to receive the treatment they want? No
  • Teaching Rounds: Teaching procedural skills
  • Rating quality of evidence and strength of recommendations: Grading quality of evidence and strength of recommendations for diagnostic tests and strategies

• Lancet, 17 maggio
  • Trastuzumab: possible publication bias

• JAMA, 14 maggio
  • Comparison of Change in Quality of Care Between Safety-Net and Non–Safety-Net Hospitals
  • The Wisdom and Justice of Not Paying for "Preventable Complications"

• PLoS Med, 13 maggio
  • Communicating the Results of Clinical Research to Participants: Attitudes, Practices, and Future Directions

• BMJ, 10 maggio
  • Personal electronic health records: MySpace or HealthSpace?
  • Rating quality of evidence and strength of recommendations: Going from evidence to recommendations

• N Engl J Med, 8 maggio
  • Etiquette-Based Medicine

• CMAJ, 6 maggio
  • Developing the evidence for evidence-based practice

• BMJ, 3 maggio
  • What is the placebo worth?
  • Problem based learning
  • Who wrote that article?
  • Rating quality of evidence and strength of recommendations: What is "quality of evidence" and why is it important to clinicians?
  • Quality Improvement Report: A framework for tobacco control: lessons learnt from Veterans Health Administration
  • The thinking doctor’s guide to placebos

• PLoS Med, 29 aprile
  • Better Reporting, Better Research: Guidelines and Guidance in PLoS Medicine
  • Standardising Outcomes in Paediatric Clinical Trials
  • A Systematic Review of Studies That Aim to Determine Which Outcomes to Measure in Clinical Trials in Children

• BMJ, 26 aprile
  • Patient and public involvement in clinical trials
  • How can quality of health care be safeguarded across the European Union?
  • GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
  • Making a difference: running the gauntlet to improve health care

• N Engl J Med, 24 aprile
  • Trying Times at the FDA — The Challenge of Ensuring the Safety of Imported Pharmaceuticals
  • Playing "Kick the FDA" — Risk-free to Players but Hazardous to Public Health
  • Full Disclosure and the Funding of Biomedical Research

• JAMA 23 aprile
  • FDA Guidance on Off-Label Promotion and the State of the Literature From Sponsors
  • Preserving Confidentiality in the Peer Review Process

• CMAJ, 22 aprile
  • Serious adverse events in academic critical care research

• Lancet, 19 aprile
  • Stopping trials early for benefit: too good to be true

• BMJ, 19 aprile
  • Darzi’s review of quality of care in the NHS
  • Internal and external validity of cluster randomised trials: systematic review of recent trials
  • Competent Novice: Confidentiality

• N Engl J Med, 17 aprile
  • Pharmaceutical Promotion to Physicians and First Amendment Rights
  • Electronic Health Records, Medical Research, and the Tower of Babel

• JAMA, 16 aprile
  • Guest Authorship and Ghostwriting in Publications Related to Rofecoxib: A Case Study of Industry Documents From Rofecoxib Litigation
  • Reporting Mortality Findings in Trials of Rofecoxib for Alzheimer Disease or Cognitive Impairment: A Case Study Based on Documents From Rofecoxib Litigation
  • Impugning the Integrity of Medical Science: The Adverse Effects of Industry Influence

• Ann Intern Med, 15 aprile
  • The International Pharmaceutical Market as a Source of Low-Cost Prescription Drugs for U.S. Patients

• BMJ, 12 aprile
  • Public Policy: Does the NHS really need a constitution?
  • Competition and integration in the English National Health Service
  • Teaching Rounds: The self critical doctor: helping students become more reflective

• JAMA, 9 aprile
  • When Should Data and Safety Monitoring Committees Share Interim Results in Cardiovascular Trials?

• Lancet, 5 aprile
  • A new initiative and invitation for health monitoring, tracking, and evaluation
  • Doctors' standard of proof rejected by lawyers?
  • EQUATOR: reporting guidelines for health research
  • Global Health Tracking. Health metrics and evaluation: strengthening the science

• BMJ, 5 aprile
  • Effects of gender on performance in medicine
  • Are there too many female medical graduates? Yes
  • Are there too many female medical graduates? No

• N Engl J Med, 3 aprile
  • Regulating Off-Label Drug Use — Rethinking the Role of the FDA
  • Options for Slowing the Growth of Health Care Costs

• JAMA, 2 aprile
  • Newly Approved Does Not Always Mean New and Improved

• Lancet 30 marzo
  • Assuring trial safety for children

• BMJ, 30 marzo
  • Over the counter medicines: proceed with caution
  • Teaching Rounds: Role modelling—making the most of a powerful teaching strategy
  • Why promote the findings of single research studies?

• N Engl J Med, 27 marzo
  • Drug-Review Deadlines and Safety Problems

• JAMA, 26 marzo
  • The Rational Clinical Examination. What Type of Urinary Incontinence Does This Woman Have?
  • Surrogate End Points and FDA Approval: A Tale of 2 Lipid-Altering Drugs

• CMAJ, 25 marzo
  • The need for an Institute of Continuing Health Education
  • The effect of privacy legislation on observational research

• Arch Intern Med, 24 marzo
  • Better Outcomes for Patients Treated at Hospitals That Participate in Clinical Trials
  • Treatment Success in Cancer New Cancer Treatment Successes Identified in Phase 3 Randomized Controlled Trials Conducted by the National Cancer Institute–Sponsored Cooperative Oncology Groups, 1955 to 2006

• Lancet, 22 marzo
  • Educating health professionals: the Avicenna project

• BMJ, 22 marzo
  • Observational evidence for determining drug safety
  • Prediction of citation counts for clinical articles at two years using data available within three weeks of publication: retrospective cohort study

• Med J Aust, 18 marzo
  • Consent in paediatric research: an evaluation of the guidance provided in the 2007 NHMRC National statement on ethical conduct in human research

• BMJ, 15 marzo
  • Evaluating laboratory diagnostic tests
  • Genetic tests for common diseases: new insights, old concerns
  • Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: meta-epidemiological study

• JAMA, 12 marzo
  • The Rational Clinical Examination. Does This Patient Have Bacterial Peritonitis or Portal Hypertension? How Do I Perform a Paracentesis and Analyze the Results?
  • Instant Mobile Communication, Efficiency, and Quality of Life
  • The Science of Improvement

• PLoS Med, 11 marzo
  • Observational Research, Randomised Trials, and Two Views of Medical Science

• Lancet, 8 marzo
  • Clinical knowledge: from access to action

• JAMA, 5 marzo
  • Who Really Pays for Health Care?: The Myth of "Shared Responsibility"
  • Financial Support of Continuing Medical Education
  • Commercial Features of Placebo and Therapeutic Efficacy

• PLoS Med, 4 marzo
  • Could an Open-Source Clinical Trial Data-Management System Be What We Have All Been Looking For

• Ann Intern Med, 4 marzo
  • Improving Patient Care. Performance Measurement in the Small Office Practice: Challenges and Potential Solutions

   

• BMJ, 16 febbraio

  • Quality failures in the NHS

  • Stronger European medical research

  • Use of randomised trials to decide when to monitor response to new treatment

  • Teaching when time is limited

• Lancet, 16 febbraio

  • The Wellcome Trust: an unsung hero in health research

• JAMA, 13 febbraio

  • Responses of Medical Schools to Institutional Conflicts of Interest

  • Effectiveness and Efficiency of Root Cause Analysis in Medicine

  • Medical Challenges of Improving the Quality of a Longer Life

  • Academic Medical Centers and Financial Conflicts of Interest

• CMAJ, 12 febbraio

  • Comparison of provincial prescription drug plans and the impact on patients' annual drug expenditures

  • Moving from opacity to transparency in pharmaceutical policy

  • Optimizing the use of prescription drugs in Canada through the Common Drug Review

• BMJ, 9 febbraio

  • Involving users in developing health services

  • Improving access to research data in Europe

  • Payment for performance in health care

  • Assessing the promise of user involvement in health service development: ethnographic study

• Lancet, 9 febbraio

  • The pitfalls and rewards of peer review

  • The dilemma of data-safety monitoring: provision of significant new data to research participants

28 gennaio - 3 febbraio

• BMJ, 2 febbraio

  • How do we get the measure of patient care?

  • European regulatory agencies should employ full time statisticians

  • Value based pricing for NHS drugs: an opportunity not to be missed?

• JAMA, 30 gennaio

  • Improving Patient Safety by Taking Systems Seriously

  • Effectiveness of Drug-Eluting Stents in Real-World Patients

• CMAJ, 29 gennaio

  • Effectiveness of paroxetine in the treatment of acute major depression in adults: a systematic re-examination of published and unpublished data from randomized trials

   

• Arch Intern Med, 28 gennaio

  • Generalizability of the Results of Randomized Trials

  • Variations Between Clinical Trial Participants and Medicare Beneficiaries in Evidence Used for Medicare National Coverage Decisions

21 - 27 gennaio

• J Gen Intern Med, gennaio 2008

  • Theme Issue. New Medical Technologies: The Potential and Pitfalls of Innovation

• Lancet, 26 gennaio

  • CONSORT for reporting randomised trials in journal and conference abstracts

  • Retraction—A growing, bleeding, violet mole

  • Narrative evidence based medicine

• BMJ, 26 gennaio

  • Mandatory disclosure of trial results for drugs and devices

  • Safer by design

• JAMA, 23 gennaio

  • Does Having More Physicians Lead to Better Health System Performance?

  • Assessing Quality of Care: Knowledge Matters

• PLoS Med 22 gennaio

  • CONSORT for Reporting Randomized Controlled Trials in Journal and Conference Abstracts: Explanation and Elaboration

• Med J Aust, 21 gennaio

  • Why do interns make prescribing errors? A qualitative study

  • The national inpatient medication chart: critical audit of design and performance at a tertiary hospital

14 - 20 gennaio

• BMJ, 19 gennaio

  • Maximising research opportunities of new NHS information systems

  • Getting the best from research funding

  • Shifting the focus in fracture prevention from osteoporosis to falls

  • Drugs for pre-osteoporosis: prevention or disease mongering?

• Lancet, 19 gennaio

  • Drug company trials come under increasing scrutiny

   

• N Engl J Med, 17 gennaio

  • Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy

• Ann Intern Med, 15 gennaio

  • Systematic Review: The Evidence That Publishing Patient Care Performance Data Improves Quality of Care

  • What Can We Say about the Impact of Public Reporting? Inconsistent Execution Yields Variable Results

• Arch Intern Med, 14 gennaio

  • Participants in Phase 1 Oncology Research Trials: Are They Vulnerable?

  • Reporting Medical Errors to Improve Patient Safety: A Survey of Physicians in Teaching Hospitals

7 - 13 gennaio

• BMJ, 12 gennaio

  • Parliamentary review asks NICE to do better still

  • On the trail of quality and safety in health care

• JAMA, 9/16 gennaio

  • Transforming Clinical Practice Guidelines Into Legislative Mandates: Proceed With Abundant Caution

  • The Meaning of Translational Research and Why It Matters

• Med J Aust, 7 gennaio

  • Do advertisements in clinical software influence prescribing?

  • The effect of advertising in clinical software on general practitioners’ prescribing behaviour

  • Commercialism, choice and consumer protection: regulation of complementary medicines in Australia

  • Paying for costly pharmaceuticals: regulation of new drugs in Australia, England and New Zealand

  • Does Enhanced Primary Care enhance primary care? Policy-induced dilemmas for allied health professionals
  • National health reform needs strategic investment in health services research

31 dicembre 2007 - 6 gennaio 2008

• BMJ, 5 gennaio

  • Non-drug industry funded research

  • Reducing hospital admissions

  • Doctor takes "march of shame" to atone for drug company payments

  • Heed the data when results are not significant

  • Effect of European Clinical Trials Directive on academic drug trials in Denmark: retrospective study of applications to the Danish Medicines Agency 1993-2006

• Lancet, 5 gennaio

  • The ethics of passer-by diagnosis

• PLoS Med, 3 gennaio

  • In the Era of Systematic Reviews, Does the Size of an Individual Trial Still Matter

  • The Cost of Pushing Pills: A New Estimate of Pharmaceutical Promotion Expenditures in the United States

• CMAJ, 1 gennaio

  • Is it time for another medical curriculum revolution?

  • Hospital volume and patient outcomes in pulmonary embolism

    • Should we regionalize the management of pulmonary embolism? 

  • The effects of problem-based learning during medical school on physician competency: a systematic review

    • Problem-based learning makes a difference. But why?

  • Systematic evaluation of errors occurring during the preparation of intravenous medication

    • Medication errors: the human factor

• Ann Intern Med, 1 gennaio

  • Achieving a High-Performance Health Care System with Universal Access: What the United States Can Learn from Other Countries

  • Learning from the Health Care Systems of Other Countries

• JAMA, 1 gennaio

  • Publication of Clinical Trials in JAMA: Information for Authors

24 - 30 dicembre

• N Engl J Med, 27 dicembre

  • Comparing Physicians on Efficiency

  • Is Quality Improvement Improving Quality? A View from the Doctor's Office

• JAMA, 26 dicembre

  • The Rational Clinical Examination. Does This Child Have a Urinary Tract Infection?

17 - 23 dicembre

• BMJ, 22 dicembre

  • Christmas Issue

• N Engl J Med, 20 dicembre

  • Outcomes of Care by Hospitalists, General Internists, and Family Physicians

  • The Hospitalist Movement — Time to Move On

• JAMA, 19 dicembre

  • Nonpayment for Harms Resulting From Medical Care: Catheter-Associated Urinary Tract Infections

• Ann Intern Med, 18 dicembre

  • Update on the Methods of the U.S. Preventive Services Task Force: Estimating Certainty and Magnitude of Net Benefit

10 - 16 dicembre